6/4/2023 0 Comments Benzo overdose antidote![]() ![]() Journal of Toxicology-Clinical Toxicology 2004 42(2):209-216. Should a benzodiazepine antagonist be used in unconscious patients presenting to the emergency department? Resuscitation 2007 74(1):27-37. Because it is not in the benzodiazepine chemical class, Buspirone is not likely to cause dependence, but it can take time to work. Some people are given an anti-anxiety drug called Buspirone to help relieve anxiety. Treatment of benzodiazepine overdose with flumazenil. Flumazenil, an antidote for a benzo overdose, is sometimes used to alleviate withdrawal symptoms. The flumazenil in benzodiazepine intoxication multicenter study group.QRS prolongation on the ECG to suggest a possible co-ingestion with a sodium channel blocking drug (i.e.Known or suspected benzodiazepine dependance.Known or suspected co-ingestion of a pro-convulsant.This decision needs to be weighed up with the ability for a ward to manage an infusion and with large adult ingestions it can be easier, quicker and potentially safer to intubate and transfer to ICU Sometimes a flumazenil infusion is warranted.Re-sedation is likely to occur at 90 minutes whereupon further doses will be required.1, 3 Benzos are central nervous system (CNS) depressants that increase the effects of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) to decrease or calm certain nervous system activity. ![]()
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